Neuropathy is when damage or dysfunction occurs to the nervous system. This damage normally happens to the peripheral nerves that exist outside of the brain and spinal cord. This is referred to as peripheral neuropathy and is the most common form of the condition. Neuropathy generally occurs in the hands and the feet, but other parts of the body can also be affected. While many treatments for this disorder fall short, some studies suggest that neuropathy stem cell therapy may help treat the problem at its source.

Your peripheral nervous system is a network of nerves outside of your central nervous system which is made up of your brain and spinal cord. The nerves in your peripheral nervous system send signals to your brain, and when these nerves are damaged, the damage disrupts the signals sent to your brain.

Neuropathy Stem Cell Therapy for Chronic Pain

Stem cell therapy may provide pain relief for chronic pain and nerve injury

Neuropathy stem cell therapy is an exciting new treatment for neuropathy that involves using stem cells to rebuild the nerve cells, called neurons. The basis of neuropathy stem cell therapy is how stem cells can transform themselves (differentiate) into completely different types of cells in the human body. This ability makes neuropathy stem cell therapy a very exciting possibility.

Stem cells sourced from patients are typically taken from blood, bone marrow or in fatty tissues. The symptoms of this chronic pain include severe and debilitating pain and tingling sensations. Electrical Nerve Stimulation Techniques such as transcutaneous electrical nerve stimulation (TENS) and peripheral nerve field stimulation (PNFS) can relieve chronic neuropathic pain by delivering mild electrical currents to the affected nerves.

Stem cell therapy has several advantages over traditional treatment options for neuropathy, such as pain relief medications, anti-seizure medications, and physical therapy. In this case, stem cell therapy involves the use of stem cells to regrow damaged nerve cells while improving nerve function and relieving neuropathic symptoms.


Neuropathic pain may result from damaged nerve cells in the feet and hands

Neuropathy is a surprisingly common affliction with nearly 30% of Americans suffering from it. The condition affects people of all ages. However the older you are, the more of a risk you have of contracting neuropathy.

Right around 8% of adults over the age of 65 suffer from some form of neuropathy and in the United States, the most common risk factors are diabetes, metabolic syndrome, and heavy alcohol use.  Certain professions that require highly repetitive motions have a greater chance of contracting a form of neuropathy called mononeuropathy.

Sometimes neuropathies will come on slowly and develop over time, while some will happen more rapidly and continue to get worse as time goes on. Out of the over 100 different types of neuropathies, each one has its own particular onset time and progression. The progression of your neuropathy also has a lot to do with what nerves were damaged, how they were damaged, and the underlying cause of the condition.

What Triggers Neuropathic Pain?

Transplanted bone marrow-derived mesenchymal stem cells can modulate microglial activation. Neuropathic pain can be triggered by central or peripheral nerve injury. There are several other red flags that you can look for when choosing a stem cell treatment facility. The nerve fibers distal to the injury site break down and are cleared away by immune cells

Neural stem cells (NSCs) are a class of pluripotent cells with division potential, self-renewal ability, and the capability of differentiating into neurons, astrocytes, and oligodendrocytes.

Peripheral neuropathy affects the body’s nerves, with causes ranging from diabetes and autoimmune disorders to excess alcohol use and vitamin deficiencies. Successful reduction of neuropathic pain associated with spinal cord injury via of a combination of intrathecal hydromorphone and ziconotide


Diabetic neuropathy is a common cause of nerve damage, reducing nerve function

The number one cause of neuropathy is diabetes. Upwards of 70% of people who suffer from diabetes have some form of neuropathy.  The most common occurrence of neuropathy that is a result of diabetes is called small fiber neuropathy which causes a painful burning in the hands and the feet. Another common cause of neuropathy is trauma.

Any sort of compression of the nerves due to repetitive stress and the narrowing of the space through which nerves run can cause neuropathy. Injuries from car accidents, falls, broken bones, and sports are common forms of trauma that will cause neuropathy. Stem cell therapy may help address nerve damage and restore nerve function.


Some medicines can cause chronic neuropathic pain

Some other less common causes of neuropathy are autoimmune disorders, infections, kidney, liver disorders, and tumors. Any kind of condition that will put pressure on the nerves and invade the space that they need to send and receive signals can cause neuropathy.

Some medicines and poisons have been documented to cause a form of neuropathy as well. Cancer treatments such as chemotherapy and radiation can cause damage to peripheral nerves, as well as exposure to toxic substances such as lead and industrial chemicals.


The signs and symptoms of neuropathy have a lot to do with what nerves were damaged in your body and how that damage occurred. Some of the most common symptoms include a tingling, pins & needles feeling in the hands and feet that are often accompanied by numbness. This numbness can be so severe that you can even experience a loss of function in the affected extremities.

Another symptom is a sharp, burning, electric-like pain that can be so severe that some doctors will even prescribe opiates for the pain. This pain will often change in sensation and go from severe, especially at night, to numbness and an inability to feel anything at all in the affected areas, then this can change to an extreme sensitivity to touch and then back again.

Some other signs and symptoms of neuropathy are cramps and spasms, low blood pressure or an abnormal heart rate which will cause dizziness when standing up and lightheadedness. Sometimes sufferers will experience bladder and digestion problems, sexual dysfunction, and weight loss.


What research says about cell transplantation injections and nerve regeneration

With the strict regulations and guidelines regarding stem cell research, to date, there hasn’t been a tremendous amount of research done. Please note that the FDA has not cleared stem cells for use as a treatment for neuropathy. However, the studies completed and the results of those experiments are very promising. You can learn about some of those studies below.


The first study we will look at is from the Journal of Pain Research, (E Russell Vickers, 2014). In this study, ten female subjects suffering from neuropathy received mesenchymal stem cells (MSCs) harvested from their own bodies. Each subject had been experiencing neuropathic pain and symptoms from 4 months to 6 and a half years.

The results of the experiment showed that after 6 months most of the subjects showed reduced pain intensity scores and a reduced need for medication. The conclusion of the study states that “administration of stem cells for neuropathic trigeminal pain significantly reduced pain intensity at 6 months and is a safe and well-tolerated intervention.”


In a publication by Stem Cells International, (Meichen Liu, 2020), the researchers collected and reviewed all the experimental, clinical, and trial articles on stem cell research for neuropathic pain for the last 10 years. They then analyzed and summarized the general efficacy and mechanism of stem cells in the treatment of neuropathic pain. They summarized the conclusion that the mechanism of neuropathic pain is extremely complex and the standard treatments and drugs for the condition do not achieve good results.

Furthermore, they found in their research that neuropathy stem cell therapy plays “multiple roles” when it comes to the peripheral, central, and spinal cord nervous systems. These roles show that stem cells “significantly reduce the occurrence of clinical symptoms including spontaneous pain, and hyperalgesia.”


Another exciting study by the International Journal of Molecular Sciences looks at stem cells’ ability to control and influence the inflammation of the neurons that happens when suffering from neuropathy. (Joshi, 2021). In this review, the researchers really break down the stem cell mechanisms including neuromodulation in treating neuropathic pain. The conclusion of this study was much like the rest as researchers found that “The intensity of NP was also significantly and gradually improved after the first BMSC (MSCs)”


Cell transplantation may help address nerve damage due to diabetic neuropathy

Neuropathy stem cell therapy is available at Stem Cells LA. Our doctors are here to answer any questions about stem cells, neuropathy, and the research supporting the procedure. We’ve performed stem cell treatments for neuropathy and understand the proper administration of the stem cells regarding the disorder.

Even if you are not ready to have a sit-down consolation with one of our doctors, and just want to have a conversation about possible treatments, call us today and we will answer any questions that you may have. We encourage you to read through all the articles on our blog and the cited research. Familiarize yourself with the promising aspects of neuropathy stem cell therapy.

Have you exhausted all other medications and treatments for your neuropathy? Tired of the constant pain from neuropathy? Call us today to find out more.


Stem Cells LA is the preferred stem cell injection provider for cell transplantation

Stem Cells LA may be able to help address your arthritis, neuropathy, orthopedic disease, anti-aging, and more. Additionally, the restorative properties of stem cell treatments may help reduce healing time. T for other procedures including hair transplants and various injuries.

At Stem Cells LA, we’re happy to provide informational services and connect you with a cell therapy provider. They’ll help you determine if stem cell therapy is right for you and your unique situation. Please keep in mind that stem cells are NOT FOR EVERYONE. Some people are candidates for stem cell procedures and others are not. We believe in the power of stem cells but at Stem Cells LA, we don’t do cures. However, we do add a very valuable tool to your wellness toolbelt.

It’s important to look into the patient experience. Your safety, privacy, and well-being are of the utmost importance to us. Remember, we’re here for you! Above all, only a qualified doctor can help you decide if stem cell therapy is right for you. We may be able to help set you up with a trusted regenerative medicine specialist. To book a consultation, call us today.

Contact Stem Cells LA for Neuropathy Stem Cell Therapy for Nerve Injury

Stem Cells LA
(310) 281-6160 1970
S. Prospect Ave., Suite 2
Redondo Beach, CA


  • E Russell Vickers, E. K. (2014). A preliminary report on stem cell therapy for neuropathic pain in humans. Journal of Pain Research.

  • Joshi, H. P. (2021). Stem Cell Therapy for Modulating Neuroinflammation in Neuropathic Pain. International Journal of Molecular Sciences.

  • Meichen Liu, K. L. (2020). Stem Cells in the Treatment of Neuropathic Pain: Research Progress of Mechanism. Stem Cells International.

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